ABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents of Hedysarum polybotrys.</p><p><b>METHOD</b>Chromatographic methods were used to isolate compounds from H. polybotrys and chemical and spectral methods were used to elucidate the structures of the isolated compounds.</p><p><b>RESULT</b>Five compounds, N,N,N-trimethyl-tropaphone inner salt (hypaphorine) (1), octadecyl-3-methoxy-4-hydroxy-benzeneacrylate (2), 5,7,4'-trihydroxy-dihydroflavanone 5,7-di-O-beta-D-glucopyranoside (3), 3,4,5-trimethoxy cinnamic acid methy ester (4) and vanillic acid (5), were isolated from the roots of H. polybotrys.</p><p><b>CONCLUSION</b>Compounds 1, 2 and 3 were obtained from this plant for the first time, while compounds 1 and 2 were isolated from Hedysarum for the first time.</p>
Subject(s)
Acrylates , Chemistry , Fabaceae , Chemistry , Indoles , Chemistry , Molecular Conformation , Molecular Structure , Plant Roots , Chemistry , Plants, Medicinal , ChemistryABSTRACT
<p><b>AIM</b>To study the chemical constituents of Hedysarum polybotrys Hand.-Mazz..</p><p><b>METHODS</b>The compounds were separated with Sephadex LH-20 and silica gel column chromatography, and their structures were identified on the basis of spectral analysis.</p><p><b>RESULTS</b>Five compounds were identified as hedysalignan A (1), isoliquiritigenin (2), formononetin (3), calycosin (4) and ononin (5).</p><p><b>CONCLUSION</b>Hedysalignan (1) is a new compound and the others were obtained from the plant for the first time.</p>
Subject(s)
Chalcone , Chemistry , Chalcones , Drugs, Chinese Herbal , Chemistry , Fabaceae , Chemistry , Furans , Chemistry , Glucosides , Chemistry , Isoflavones , Chemistry , Molecular Conformation , Molecular Structure , Plant Roots , Chemistry , Plants, Medicinal , ChemistryABSTRACT
<p><b>OBJECTIVE</b>To summarize the pharmacological function of oleanolic acid.</p><p><b>METHOD</b>Based on the documents and related achievements, the pharmacological function and its mechanism including its clinical use were summed up.</p><p><b>RESULT AND CONCLUSION</b>Oleanolic Acid is a natural chemical which has wide-ranging function and abundant source. But we should place the emphasis on improving its biotic utilization and effect on clinical treatment.</p>
Subject(s)
Animals , Humans , Adjuvants, Immunologic , Pharmacology , Antineoplastic Agents, Phytogenic , Pharmacology , Antiviral Agents , Pharmacology , Hepatitis, Viral, Human , Drug Therapy , Hypoglycemic Agents , Pharmacology , Oleanolic Acid , Pharmacology , Phytotherapy , Plants, Medicinal , ChemistryABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents in the root of Hedysarum polybotrys Hand.-Mazz..</p><p><b>METHOD</b>The constituents were isolated by Sephadex LH-20 and silica gel column chromatography, and their structures were identified on the basis of spectral analysis.</p><p><b>RESULT</b>Five compounds, medicarpin (I), 3-hydroxy-9-methoxycoumestan (II), 3, 9-dihydroxycoumestan (III), beta-sitosterol (IV), beta-sitosterol-3-O-beta-D-glucoside (V) were obtained.</p><p><b>CONCLUSION</b>Compounds II, III, V were obtained from the plant for the first time.</p>
Subject(s)
Fabaceae , Chemistry , Molecular Structure , Plant Extracts , Chemistry , Plant Roots , Chemistry , Plants, Medicinal , Chemistry , Pterocarpans , ChemistryABSTRACT
<p><b>OBJECTIVE</b>To investigate the chemical constituents from the root and rhizome of Rheum rhizastachyum.</p><p><b>METHOD</b>The compounds were isolated by column chromatography on silica gel, Sephadex LH-20, MCI-gel CHP-20P separately and their structures were elucidated by chemical and spectral technology.</p><p><b>RESULT</b>Six compounds were isolated and identified as chrysophanol, emodin, gallic acid, sucrose, 1-O-beta-D-glucopyranosyl-chrysophanols, 1-O-beta-D-glucopyranosyl-emodin.</p><p><b>CONCLUSION</b>All the compounds were obtained from this plant for the first time.</p>